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The algorithm includes the following steps: treatment of fetuses with isolated severe LUTO within days from the first diagnosis (from as early as 12 weeks of gestation onward); karyotyping.
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Overall, 5 of 9 LUTO fetuses (55%) undergoing VAS with the Somatex ® intrauterine shunt system showed long-term survival beyond the neonatal period of 28 d (5/9; 55%) with varying morbidity. Fetal therapy of LUTO (lower urinary tract obstruction) - a follow-up observational study
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Fetal lower urinary tract obstruction (LUTO), which often results in marked perinatal morbidity and mortality, is caused by a heterogeneous group of anatomical defects that lead to blockage of the urethra. The classic prenatal presentation of LUTO includes megacystis with hydronephrosis. While mild forms of the disease can be associated with.
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Abstract. Fetal lower urinary tract obstruction (LUTO) is a serious condition, which commonly results in marked perinatal morbidity and mortality. The characteristic prenatal presentation of LUTO includes an enlarged bladder with bilateral obstructive uropathy. While mild forms of the disease result in minimal clinical sequelae, the more severe.
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Inclusion criteria of the selected studies were singleton pregnancy with severe LUTO confirmed on detailed fetal ultrasound examination. Nine studies analyzed the efficacy of vesico-amniotic shunt performed in the second trimester. The overall estimate survival was higher in the vesico-amniotic shunt group compared to the conservative group (OR.
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LUTO occurs when the flow of urine is blocked from exiting the body at the level of the lower urinary tract. When LUTO occurs, all parts of the urinary tract that lie above the obstruction may become swollen with urine that cannot drain. Over time this blockage can lead to permanent kidney damage. When urine can no longer be drained, the fluid.
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Lower urinary tract obstruction (LUTO), also known as bladder outlet obstruction (BOO), is a rare condition which occurs more commonly in males than females. LUTO is a blockage either at the base of the bladder or at the urethra, which is the tube that drains urine from the bladder. Depending on the severity of the blockage, the drainage of.
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Lower urinary tract obstruction (LUTO) refers to a blockage in the urinary tract that restricts or prevents the release of urine from the bladder. Accumulation of urine within the kidneys and bladder throughout pregnancy results in permanent damage to these organs. If urine cannot exit the body, the amount of surrounding amniotic fluid.
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babies with LUTO die, even if fetal therapy was performed. How sick a baby will be after birth depends on how severe the lung and kidney damage are, and depends on the cause of the baby's LUTO. For these reasons, it is important to have a thorough evaluation of a baby with LUTO in the NICU, and close monitoring by the baby's pediatrician.
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Lower urinary tract obstruction (LUTO) is a complex fetal genitourinary disorder associated with significant morbidity and mortality, which requires diagnostic and management advancement to improve fetal outcomes. While LUTO is estimated to occur in only 2.2-3.3 cases per 10,000 [ 1, 2 ], it can have a devastating impact on the fetus and on.
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Fetal lower urinary tract obstruction (LUTO) is a condition that occurs when the baby's urethra, the tube that transports urine from the bladder to the outside of the body during urination (Figure 1), becomes partially or completely blocked. The condition is serious for several reasons. It can cause the baby's bladder to become enlarged and.
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A final diagnosis was achieved in 143 cases, including 124 of LUTO and 19 reclassified after birth as non-obstructive megacystis. The optimal bladder volume cut-off for prediction of LUTO was 35 cm 3 (area under the curve (AUC) = 0.7, P = 0.03). The clinical score formulated on the basis of the multivariate analysis included fetal sex, degree.
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Fetal lower urinary tract obstruction (LUTO) affects ~2-3 out of 10,000 fetuses with a wide spectrum of severity 1.LUTO diagnosis can be either prenatal or postnatal, with a 1:1 ratio, as.
