Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus
A Reed naevus is a very dark pigmented melanocytic naevus with spindle-shaped dermal melanocytes on histology. It was first reported by dermatologist Richard Reed in 1975. It is also known as a spindle cell naevus. Reed naevus is sometimes classified as a kind of Spitz naevus; the spindle-shaped cells of the Reed naevus may coexist with the.
Reed Nevus (Pigmented Spindle Cell Nevus) in an 11MonthOld Japanese Infant
Differential diagnosis of Spitz and Reed naevi. The differential diagnosis of Spitz and Reed naevi includes acquired melanocytic naevi, blue naevi and melanoma.. Spitz tumours with kinase fusions. It has recently been shown that spitzoid neoplasms harbour kinase fusions of ROS1 (17%), NTRK1 (16%), ALK (10%), BRAF (5%) and RET (3%) in a mutually exclusive pattern.
Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus
Clinically, pigmented Spitz/Reed nevi are brown to black, flat to slightly elevated, symmetrical lesions showing a relative preference for certain locations, including face, limbs and buttocks. The most relevant and peculiar feature is the starburst pattern seen by dermoscopy. This is typified by multiple streaks of pigmentation or large.
Pigmented Spindle Cell Nevus of Reed Dermatopathology
Reed nevus is considered a pigmented variant of Spitz nevus. It usually appears during childhood, adolescence or early adulthood, and commonly appears on the lower limbs of female patients. After 6 months of rapid growth, Reed nevus tends to show no more enlargements over time. The starburst pattern is the dermatoscopic hallmark of Reed nevus.
Dermoscopy of Pigmented Spitz and Reed Nevi Dermatology JAMA Dermatology The JAMA Network
The histopathologic distinction between Spitz nevus and Reed nevus is often matter of great debate. Nowadays, we distinguish two clinical variants of SN, the classical and the pigmented types, the latter include Reed nevus. The most important issue of SN is their propensity to mimic melanoma clinically, dermatoscopically and histopathologicallly.
Clinical features and natural history of SpitzReed nevus in children. Semantic Scholar
Reed naevus; Meyerson naevus is a naevus affected by a halo of eczema / dermatitis. Halo naevus or Sutton naevus has a white halo around the mole. The mole gradually fades away over several years. Spitz naevus or epithelioid cell naevus is a pink (classic Spitz) or brown (pigmented Spitz) dome-shaped mole that arises in children and young adults.
Dermpath Made Simple Neoplastic Spitz Nevus and Reed Nevus
However, to date, many textbooks or atlases of dermatology or histopathology assert that Reed nevus is a variant of Spitz nevus [4,6,21-25]. According to Argenziano et al, a dermatopathologic distinction between pigmented Spitz and Reed nevus is difficult, not reproducible and maybe clinically useless.
Dermoscopy of Pigmented Spitz and Reed Nevi The Starburst Pattern Dermatology JAMA
The Reed Nevus or pigmented spindle cell nevus (PSCN) was first described by Reed et al. in 1975 . Its designation as a separate entity vs. a SN variant remains controversial, but is currently considered by the 2018 WHO Classification to be a "distinct variant of Spitz naevus.".
Nevo de Reed. Diagnóstico dermatoscópico de un caso PIELL Latinoamericana
'Nevus, Reed' published in 'Dermatopathology' Pigmented spindle cell nevus is a sharply demarcated and symmetrical melanocytic lesion characterized by a florid and cellular junctional component and marked melanin pigmentation (Fig. 1).The junctional aspect is composed of large and prominent nests containing uniform, spindled melanocytes arranged in fascicles with a characteristic vertical.
Naevus van Reed (pigmented spindle cell nevus)
The Spitz naevus (syn. spindle cell naevus, epithelioid cell naevus, juvenile melanoma) is a variant of a compound naevus and is most commonly seen in children . The pigmented spindle cell naevus of Reed (PSCNOR) is a variant of a compound or occasionally a junctional naevus. There is debate as to whether the PSCNOR is an entity in its own.
Reed nevus on the finger (A) Clinical features of the lesion. (B)... Download Scientific Diagram
Update on dermoscopy of Spitz/Reed naevi and management guidelines by the International Dermoscopy Society Br J Dermatol. 2017 Sep;177(3):645-655. doi: 10.1111/bjd.15339.. Nevus, Epithelioid and Spindle Cell / pathology Nevus, Epithelioid and Spindle Cell / therapy*.
Pigmented Spindle Cell Nevus of Reed Dermatopathology
The clinical-dermatoscopic-histological correlation of excised Spitz/Reed nevi revealed overlapping histopathological features among lesions displaying distinct dermatoscopic patterns ( Figures 1 - 3 ). Among lesions with histopathological atypia (16/47, 34.0%), all dermatoscopic patterns were represented, although the atypical/multicomponent.
Evolution of Reed Nevi Dermoscopic Pattern in Childhood Dermatology JAMA Dermatology JAMA
In contrast to Spitz nevus, the indicators of a congenital origin of Reed nevus are poor. The outstanding reports on agminated or systematized Reed nevi, or Reed nevus as constituent of a combined nevus, rather suggest a histogenetic event compatible with what is regarded to be a truly acquired melanocytic nevus and might represent another clue.
Dermoscopy Made Simple Reed Nevus
Pigmented spindle cell nevus (PSCN) of Reed is a morphologic variant of Spitz and may be very diagnostically challenging, having histologic features concerning for melanoma. Their occurrence in younger patients, lack of association to sun exposure, and rapid early growth phase similar to Spitz nevi suggest fusions may also play a significant.
Pigmented Spindle Cell Nevus of Reed Dermatopathology
Reed nevus (also known as pigmented spindle cell nevus of Reed) is an acquired, benign, melanocytic lesion most frequently classified as a variant of a Spitz nevus. A Reed nevus typically presents as an asymptomatic, single, 2-8 mm, dark brown to black macule or papule on the lower extremities of young adults. The lesion may also be found in.
Starburst dermoscopic pattern of Reed nevus Download Scientific Diagram
A Reed nevus is a dark brown or black, raised, dome-shaped mole that most often affects women. These moles can grow quickly and may be mistaken for melanoma. These moles can grow quickly and may.
